Journal of SARS-CoV-2 Research https://spphllc.com/Sarc-CoV-2 <p><img style="float: left; margin-right: 30px;" src="https://spphllc.com/public/site/images/admin/%D0%B2%D1%84%D1%8B.jpg" alt=""></p> <p><strong>ISSN: 2768-7953</strong></p> <p><strong>Scope:&nbsp;</strong>The <strong>Journal of SARS-CoV-2 Research (JSCR) </strong>is an open-access medical journal that publishes original research, reviews, case reports, and letters covering a broad field of research relevant to SARS-CoV-2. We intend to publish articles that are stimulating to read, educate, and inform readers with the most up-to-date research relevant to the journal's scope.<br>Papers about short- and long-term outcomes of the disease, immunization-related papers, and new treatments will be given priority.<br>The journal's main aim is to spread new knowledge and findings of SARS-CoV-2 among the medical community in a timely manner.<br>Open discussion and opinions are welcome. Indexed in ROAD: https://portal.issn.org/resource/ISSN/2768-7953.</p> SciencePower Publishing House, LLC en-US Journal of SARS-CoV-2 Research 2768-7953 <p>Authors who publish with this journal agree to the following terms:<br><br>Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.<br><br>Authors are permitted and encouraged to post links to their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.</p> IMPACT OF COVID-19 PANDEMIC ON MENTAL HEALTH AND SOCIAL SUPPORT AMONG ADULTS IN THE AGE GROUP OF 18 TO 60 YEARS RESIDING IN THE FARASAN REGION, KINGDOM OF SAUDI ARABIA https://spphllc.com/Sarc-CoV-2/article/view/91 <p><strong><em>Introduction.</em></strong><strong>&nbsp;</strong>The COVID-19 pandemic has brought into focus the mental health of various affected populations. It is known that the prevalence of epidemics accentuates or creates new stressors, including fear and worry for oneself or loved ones, constraints on physical movement and social activities due to quarantine, and sudden and radical lifestyle changes.</p> <p><strong><em>Material and methods</em></strong><strong>. </strong>This study aimed to assess the impact of the COVID-19 pandemic on mental health and social support among adults in the age group of 18 to 60 years residing in the Farasan community, Kingdom of Saudi Arabia. Through a quantitative survey approach and descriptive design, the 48 adults were selected by the non-probability purposive sampling method. Initially, personal information was obtained. The self-administered questionnaire on the Impact of Event Scale-Revised (IES-R) was used, which was validated in Arabic to determine the extent of psychological impact after exposure to a public health crisis. The modified rating scale was used to assess the negative mental health impact; and impacts on social and family support, need-based Education about COVID-19, and its coping mechanism through pamphlets.</p> <p><strong><em>Results.</em></strong> The results of the study were presented as the Psychological Impact of COVID-19 pandemic by "Impact of Event" total score (mean±SD), which was 36.4±17.31, "Intrusion" domain was 12.83±6.192, "Avoidance" domain was 13.19±6.81, while "Hyperarousal" domain was 10.38 ± 4.31. Also, 6 (12.5%) of the sample suffered a severe impact, 10 (20.8%) were moderately affected, and 12 (25%) were mildly affected. The younger people (18-30 years old), females, and university-educated people reported a higher psychological impact than older males or people with post-graduate degrees. Persons working in the medical field reported a lower psychological impact than others. Also, people who live in urban areas or have chronic diseases had higher psychological impact scores.</p> <p><strong><em>Conclusion.</em> </strong>Age and rural residency were negative predictors of the "Impact of Event" scores. At the same time, the female gender or the presence of chronic conditions was a positive predictor for the high "Impact of Event" score. Positive impacts had and family and social support.</p> <p><strong>&nbsp;</strong></p> Santhi Muttipoll Dharmarajlu Ruba Bahkali Reham Khaled Zamzam Khamis Mariam Abdullah Hamdi Tagheeed Taher Sumaili Copyright (c) 2022 Journal of SARS-CoV-2 Research https://creativecommons.org/licenses/by/4.0 2022-06-06 2022-06-06 2 25 31 10.36013/sarc-cov-2.v2i.91 SECONDARY INFECTIONS IN THE FAMILY FROM PRIMARY CASES OF COVID-19 BREAKTHROUGH INFECTIONS IN FULLY VACCINATED OR NOT FULLY VACCINATED PEOPLE. TWO DOSES MODESTLY REDUCE FAMILY TRANSMISSION BUT DOES NOT ELIMINATE IT https://spphllc.com/Sarc-CoV-2/article/view/85 <p><strong>Background </strong><span data-preserver-spaces="true">It is unclear whether vaccination of individuals against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) protects members of their households.</span></p> <p><strong><span data-preserver-spaces="true">Objective </span></strong><span data-preserver-spaces="true">Epidemiological evaluation of SARS-CoV-2 transmissibility from fully and incompletely vaccinated index cases with COVID-19 breakthrough infection to initially uninfected family members (secondary attack rate)</span></p> <p><strong><span data-preserver-spaces="true">Methodology </span></strong><span data-preserver-spaces="true">An observational, longitudinal, and prospective study of all families with a primary case of COVID-19 breakthrough infection in fully vaccinated or not fully vaccinated people and at least one COVID-19 secondary case in family members was conducted from February to November 2021 in a general medicine office in Toledo, Spain. Clinical and epidemiological variables were compared between secondary cases of primary cases of COVID-19 breakthrough infection in fully vaccinated people versus secondary cases of primary cases of COVID-19 breakthrough infection in not fully vaccinated people.</span></p> <p><strong><span data-preserver-spaces="true">Results </span></strong><span data-preserver-spaces="true">Twenty-five index cases (25 families; 84 people) were included, 13 fully vaccinated, which gave rise to 20 secondary cases, and 12 not fully vaccinated, which gave rise to 21 secondary cases. The secondary attack rate of exposed family members to fully vaccinated primary cases were 61% (20/33), and the secondary attack rate of exposed family members to not fully vaccinated primaries was 81% (21/33).&nbsp;</span></p> <p><strong><span data-preserver-spaces="true">Conclusions </span></strong><span data-preserver-spaces="true">In the context of general medicine in Toledo (Spain), from February to November 2021 (before omicron), two doses of COVID-19 vaccine vs. only one modestly reduce family transmission but do not eliminate it.</span></p> <p>&nbsp;</p> Jose Luis Turabian Copyright (c) 2022 Journal of SARS-CoV-2 Research https://creativecommons.org/licenses/by/4.0 2022-03-20 2022-03-20 2 12 24 10.36013/sarc-cov-2.v2i.85 RISK FACTORS FOR MORTALITY IN ADULT PATIENTS WITH COVID 19 IN NORTHEAST MEXICO https://spphllc.com/Sarc-CoV-2/article/view/79 <p><strong>Introduction </strong></p> <p>The pandemic, in terms of incidence, mortality and speed of expansion, is heterogeneous, even between regions of the same country, finding differences in its clinical presentation, severity and lethality; For this reason, the research aims to: know the risk factors associated with mortality in adult patients with COVID 19.</p> <p><strong>Material and methods</strong></p> <p>Retrospective cohort study included hospitalized patients, older than 18 years, diagnosed with Covid-19 through RT-PCR test. Data collected from the electronic file and analyzed to detect differences between survivors and non-survivors, using Student's t-test and Chi-square or Fisher's exact test. The relative risk was calculated with a 95% Confidence Interval (with statistical significance p &lt;0.05.</p> <p><strong>Results</strong></p> <p>&nbsp;247 patients were studied. With a lethality of 50.20%. Arterial hypertension was the most frequent comorbidity. The oxygen supply with an invasive device was associated with a high risk of death. Tracheostomy is a high factor (p &lt;0.001). With a statistical difference in favor of the early one. The mask and the nasal tips showed a protective effect (p &lt;0.05). The most frequent symptoms were dyspnea, fever and cough without statistical difference. SatO2 at admission did show significance between both groups.</p> <p><strong>Conclusion</strong></p> <p>&nbsp;There is a difference between the risk factors in both groups. A peripheral SatO2 of &lt;90% at admission and the determination of PNC and D-DIME warrant close monitoring to avoid severe complications.</p> <p>&nbsp;</p> Oscar Manuel Berlanga Bolado Patricia Rivera Vázquez José Antonio Villalobos Silva Aristeo Avalos Míreles Héctor Zamarripa Gutiérrez Sandra Gabriela Medina Escobedo Vicente Enrique Flores Rodríguez Copyright (c) 2022 Journal of SARS-CoV-2 Research https://creativecommons.org/licenses/by/4.0 2022-01-24 2022-01-24 2 1 11 10.36013/sarc-cov-2.v2i.79